Optic Neuritis in Children in a Private  Hospital: Improving Outcomes: Paediatric Ophthamology and Strabismus

Adedayo Adio; Olubusayo O Adejumo; Benedictus G. K. Ajayi

Authors

Adedayo Adio Eleta Eye Institute, Ibadan, Oyo State, Nigeria
Olubusayo O Adejumo Eleta Eye Institute, Ibadan, Oyo State, Nigeria
Benedictus G. K. Ajayi Eleta Eye Institute, Ibadan, Oyo State, Nigeria

Abstract

Introduction: Optic neuritis is a demyelinating inflammatory disease of the optic nerve usually affecting young adults between ¹⁸ and ⁴⁵ years of age.¹ It could lead to both visual and rarely, systemic morbidity from multiple sclerosis especially in Caucasians.¹Vision loss is usually monocular, however, involvement of both eyes can occur, especially in children. ² There was no well established guidelines for treatment of optic neuritis prior to the Optic Neuritis Treatment Trial (ONTT) as some experts advocated treatment with oral prednisone alone while others recommended no treatment.^3,4The current treatment for acute optic neuritis is intravenous methylprednisolone followed by oral prednisolone.³

Author Biography

Adedayo Adio, Eleta Eye Institute, Ibadan, Oyo State, Nigeria

Department of Ophthalmology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria

References

Vimla M, Rohit S, Rubry M and Swati P. Management of Optic neuritis. Indian J Ophthalmol. 2011; 59: 117-122.

Boomer J and Siatkowsky RM. Optic neuritis in adults and children. Semin Ophthalmol. 2003; 18: 174–180.

Cleary PA, Beck RW, Anderson MM, Kenny DJ, Backlund J and Gilbert PR. Optic Neuritis Study Group: Design, methods and conduct of the Optic

Neuritis Treatment Trial. Control Clin Trials. 1993; 14:123–142

Junqing Wang, Huanfen Zhou, Limin Qin, et al., “Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study,” Journal of Ophthalmology. 2017: 1-7

Harinder SS, Vimla M, Pradeep S and Radhika T. Visual outcome after intravenous dexamethasone therapy for idiopathic optic neuritis in an Indian population: A clinical case series. Indian J of Ophthalmol.2006; 54: 177-183

Panjiyar P, Sharma AK, Shrestha GB and Shah A.A comparative evaluation between megadose intravenous dexamethasone and intravenous methyl prednisolone in the treatment outcome of optic neuritis. Journal of Chitwan medical college.2015; 5: 14

Sethi H, Menon V, Sharma P, Khokhar S and Tandon R. Visual Outcome after Intravenous Dexamethasone Therapy for Idiopathic Optic Neuritis in an Indian Population: A clinical case series . Indian J Ophthalmol 2006; 177-183.

Menon V, Mehrotra A, Saxena R and Jaffery N. Comparative evaluation of Megadose Methylprednisolone with Dexamethasone for treatment of primary typical optic neuritis. Indian J Ophthalmol 2007; 55: 355-359.

Omoti AE and Waziri-Erameh MJ. Management of optic neuritis in a developing African country. Niger Postgrad Med J. 2006; 13: 358-360

Pedro Egbe CN, Fiebai B and Ejimadu CS. Visual outcome following optic neuritis: A 5-year review. Niger J Clin Pract. 2012; 15: 311-314