Clinicopathologic Features of Epithelial Lacrimal Gland Tumors in Ibadan

Orbit and Oculoplasty

Authors

  • Oluyemi Fasina Department of Ophthalmology, University College Hospital/University of Ibadan, Ibadan, Nigeria.

Abstract

Introduction: Lacrimal gland masses account for 5 to 13% of all surgical specimens from the orbit1,2 and are traditionally classified as 50% epithelial and 50% non-epithelial in origin3 . However, recent studies1,4 have reported that the proportion of epithelial lacrimal gland tumors is lower than earlier documented. Epithelial lacrimal gland tumors comprise benign and malignant lesions with the proportion of benign tumors to malignant tumors reported to be 55% benign and 45% malignant5. However, higher proportion of benign tumors have been reported among Asians compared to Caucasians in recent studies suggesting regional variability in the pattern of distribution of these tumors6 . Hence, we prospectively studied all cases of histologically confirmed epithelial lacrimal gland tumors managed at a tertiary center in Nigeria. The objective of this study is to describe the clinical features, histopathologic profile and  treatment of epithelial lacrimal gland tumors in a homogenous black African population

Methods: Included in this study are all patients with histopathological diagnoses of epithelial tumors of the lacrimal gland managed at the Oculoplasty and Ocular oncology Unit, Eye Clinic, University College Hospital, Ibadan, Nigeria, between July 2008 and June 2018. The information recorded for the patients included their demographics, presenting symptoms and duration, findings on clinical examination, radiological investigations, operative findings, histopathological details, and post-operative management.

References

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Shields JA, Shields CL and Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1. Ophthalmology. 2004; 111(5): 997-1008

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Font RL, Smith SL and Bryan RG. Malignant epithelial tumors of the lacrimal gland. A clinicopathologic study of 21 cases. Arch Ophthalmol 1998; 116:613- 616

Bernardini FP, Devoto MH and Croxatto JO. Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol 2008;19: 409–413

Chawla B, Kashyap S, Sen S, Bajaj MS, Pushker N, Gupta K, Chandra M and Ghose S. Clinicopathologic review of epithelial tumors of the lacrimal gland. Ophthal Plast Reconstr Surg 2013; 29:440– 445

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Published

2023-03-26

How to Cite

Fasina, O. (2023). Clinicopathologic Features of Epithelial Lacrimal Gland Tumors in Ibadan: Orbit and Oculoplasty. Transactions of the Ophthalmological Society of Nigeria, 3(1). Retrieved from https://tosn.org.ng/index.php/home/article/view/176