Orbito-Ocular Tumors at the Benue State University Teaching Hospital Makurdi, Nigeria: Orbit and Oculoplasty

K Chaha; A Adekwu; T Ben-Ameh; U Ogaga

Authors

K Chaha Department of Ophthalmology, Benue State University Teaching Hospital, Makurdi
A Adekwu Department of Otorhinolaryngology, College of Health Sciences, Benue State University, Makurdi.
T Ben-Ameh Department of Ophthalmology, Benue State University Teaching Hospital, Makurdi
U Ogaga Department of Ophthalmology, Benue State University Teaching Hospital, Makurdi

Abstract

Introduction: Orbito-ocular tumours are tumours arising from the orbit and its content, and are important causes of morbidity and mortality.1 The most common intraocular malignancy globallyis choroidal melanoma in adults, and retinoblastoma in children.2,3 Orbito-ocular pathologies can cause cosmetic blemish, lead to compromise of vision and even cause death if not treated early. This is a study on the pattern of orbito-ocular tumours seen in the Benue State University Teaching Hospital.The aim of the study is to highlight the different orbito-ocular tumors and consider other demographics of such, as seen in the Benue State University Teaching Hospital, Makurdi.

Methods: The ethical committee of the hospital gave approval for the study. It is a retrospective hospital based study. All case folders of patients that had surgery for an orbito-ocular tumour in Benue State University Teaching Hospital between 2014 and 2016 were retrieved and those with a histological diagnosis were analyzed.

Results: There were 7 male(46.7%) and 8 female (53.3%)cases, with a male to female ratio of 1:1.1 One of the 15 cases( 16 eyes) had bilateral retinoblastoma. There were 4 eyes with retinoblastoma (25% of eyes).3 with squamous cell carcinoma (18.8% of eyes), and 2 cases of orbital rhabdomyosarcoma (12.5% ).The rest of the tumours were 1 each (6.25%). Ocular surface squamous neoplasia was found in 5 eyes of 5 patients(31%). Of these, 4(80% ) were HIV positive.

Views | Downloads: 30 / 19

References

C M Chuka-Okosa, N J Uche and N N Kizor-Akaraiwe: Orbito-ocular neoplasms in Enugu, South-Eastern Nigeria; West African Journal of Medicine 2008, 27 (3): 144-1447

Holland-Frei Cancer Medicine, 6th Edition

B V Castillo Jnr, L Kauffman: paediatric Tumours of North America 2003 Feb; 50(1):149-172

D Chinda, M O Samaila, E R Abah, F Garba, A L Rafindadi and A Adamu: A clinico-pathological study of orbito-ocular tumours at Ahmadu Bello University Teaching Hospital Shika-Zaria, Nigeria: a 5 –year review; Clin Cancer Invetig J 2012; 1: 145-147

Olurin MB and A O Williams: Orbito ocular tumors in Nigeria; cancer Volume30, Issue 2 August 1972: 580-587

I M Ifeanyinwa, T M Owoleye, O O Olaofe and K N Ezike: Morhpological Spectrum of Orbito-ocular Disease in a Tertiary Health Centre in Keffi, North-Central Nigeria; Advances in Medicine Volume 2015, article ID619414

O Fasina, O I Fawole and O A Ayeni: Orbito-Ocular Tumours in Ibadan, SouthWest Nigeria; West African Journal of Medicine 2014 Jul-Sep;33(3): 211-215

B A Akpe, A E Omoti and E T Iyasele. Hitopathology of Ocular Tumour Specimens in Benin City, Nigeria; Journal of Ophthalmic and Vision Research 200, 2009 4: 232-237

A B Umar, O Ochicha and Y Iliyasu: A pathologic Review of Ophthalmic Tumours in Kano, Northern Nigeria; Ngerian Journal of Basic and Clinical Sciences 2012, 9: 23-26

C C Anunobi, Akinsola F B, Abdulkarim F B, Aribaba O T, Nnoli M A and Banjo A A: Orbito-ocular lessions in Lagos; Niger Postgrad Medical J 2008; 15: 146-151

C O Bekibele and A O Oluwasola: A clinicopathological study of orbito-ocular diseases in Ibadan between 1991-1999; Afri J Med Med Sci. 2003 June; 32(2): 197-202

R Mittal, S Rath and G K Vemuganti: Ocular surface squamous neoplasia – Review of etio-pathogenesis and an update on clinico- pathological diagnosis; Saudi J Ophthalmol. 2013 Jul; 27(3): 177– 186.

Thomas J.O. Acquired immunodeficiency syndrome-associated cancers in SubSaharan Africa. Semin Oncol. 2001; 28: 198–206.

Spitzer M.S., Batumba N.H and Chirambo T. Ocular surface squamous neoplasia as the first apparent manifestation of HIV infection in Malawi. Clin Experiment Ophthalmol. 2008; 36: 422–425.