Ocular Surface Squamous Neoplasia - A Case Presentation
Keywords:
Human immunodeficiency virus, Ocular surface squamous neoplasiAbstract
Introduction: Ocular surface squamous neoplasia (OSSN) as proposed by Lee and Hirst in 1995 comprises a wide spectrum of dysplastic changes of the ocular surface epithelium.1,2 Risk factors include immunosuppression (HIV/AIDS), ocular surface HPV infections (subtypes 16 and 18), and exposure to UV light, etc.1-3 Common symptoms are growth in the eye, redness, tearing, and foreign body sensation; however, in very advanced cases, necrotizing scleritis, associated with severe pain and visual loss. It is usually unilateral and in the interpalpebral limbal stem area. Signs are fleshy conjunctival lesions with a gelatinous, leukoplakic or papillary appearance which may be flat/raised/localized/diffuse, +/-feeder conjunctival vessels.1-3 Excisional biopsy with histology gives the definitive diagnosis.1-3
References
Fasina O. Ocular surface squamous neoplasia at a tertiary eye facility, Southwestern Nigeria: a 10-year review.Int Ophthalmol 2021; 41(10):3325-3331.
Patel U, Karp CL, Dubovy SR. Update on the management of ocular surface squamous neoplasia. Current ophthalmology reports. 2021; 9(1):7-15.
American Academy of Ophthalmology series 2021-2022; section
Ophthalmic Pathology and Intraocular Tumors.
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