Central Corneal Thickness (CCT) in Open Angle Glaucoma and Glaucoma Suspects in Calabar, Nigeria

Glaucoma

Authors

  • Dennis G. Nkanga Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.
  • Affiong Andem Ibanga Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.
  • Elizabeth D. Nkanga Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar
  • Bassey A. Etim Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.
  • Kennedy Nwachukwu Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar
  • Pius O. Ogba Zerah Eye Hospital and Laser Centre, Plot 103 Ibom Layout, Calabar

Abstract

Introduction: Central Corneal Thickness (CCT) is a measurement of the thickness of the central 3mm of the cornea.[1] It has gained increased significance in glaucoma evaluation and management. This resulted from the observed relationship between CCT and intraocular pressure (IOP) levels.[2-4] CCT varies with age and also among ethnic groups. The Ocular Hypertension study found significantly thinner corneas among African Americans [5-7]. The purpose of this study was therefore to determine to what extent CCT affected IOP and thus management decisions in glaucoma patients and suspects [8,9] .

Methods: A cross sectional study design was chosen. Ethical approval was obtained from the research ethics committee of the University of Calabar Teaching Hospital (UCTH). All consecutive patients seen in the eye clinic of UCTH who were diagnosed with Chronic open angle glaucoma or as Glaucoma suspects from January 2013 to December 2013, were included after an informed consent was obtained for the study. For the purpose of this study a glaucoma suspect is defined as an adult who has one of the following findings in at least 1 eye:

  • an optic nerve or nerve fiber layer defectsuggestive of glaucoma (enlarged cup–disc ratio, asymmetric cup–disc ratio, notching or narrowing of the neuro-retinal rim, a disc hemorrhage, or suspicious alteration in thenerve fiber layer)
  • a visual field abnormality consistent withglaucoma
  • an elevated IOP greater than 21 mm Hg

Author Biographies

Dennis G. Nkanga, Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.

Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar

Affiong Andem Ibanga, Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.

Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar

Bassey A. Etim, Department of Ophthalmology, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.

Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar

References

AAO. Glaucoma. In: George A, Jane D, Christopher A, Peter A, Netland M, John R, editors. Basic and clinical science course. 2009th – 2009th ed. San-Francisco: AAO; 2009.

Goldmann H, Schmidt T. Uber Applanation tonometrie. Ophthalmologica. 1957;134:221–42.

Duane T. Intraocular Pressure: Measurement. In: Robert L, Omar P, George T, editors. Duane’s ophthalmology (DVD). 2011th ed. Philadelphia:

Lippincott Williams & Wilkins; 2011.

Brandt JD, Beiser JA, Kass MA, Gordon MO. Central corneal thickness in the Ocular Hypertension Treatment Study (OHTS). Ophthalmology. 2001; 1779– 1788.

Brandt JD, Beiser JA, Kass MA, Gordon MO. Central corneal thickness in the ocular hypertension treatment study (OHTS). Ophthalmology [Internet]. 2001;108:1779–88. Available from: http:/ /www.sciencedirect.com/science/ article/pii/S0161642001007606

Egwuonwu NNN-. Central Corneal Thickness in Nigerians: A populationbased study in Lagos State. Glaucoma Clinical Research [Internet]. 2012. p. 462. Available from: http://www.abstractsonline.com/Plan/ViewAbstract.aspx?mID=2866 &sKey=9b2e1bc9-dd59-4221-ac20-e1a3ac08b130&cKey=558adaff-0658-4b0b-8e81-85671d441063&mKey={F0FCE029-9BF8-4E7C-B48E-9FF7711D4A0E}#

Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol [Internet]. 2002;120(6):714–20; discussion 829–30.

Available from: http://www.ncbi.nlm.nih.gov/pubmed/12049575

Iyamu E, Kio F, Idu F, Osedeme B. The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma. Sierra Leone J Biomed Res [Internet]. College of Medicine and Allied Health Sciences, University of Sierra Leone; 2011;2(2):4–8.

Available from: http://www.ajol.info/index.php/sljbr/article/view/63999

Iyamu E, Ituah I. The relationship between central corneal thickness and intraocular pressure: a comparative study of normals and glaucoma subjects. Afr J Med Med Sci. 2008;37(4):345–53.

Whitacre MM, A SR, Hassanein K. Sources of error with the use of Goldmann-type tonometers. Surv Ophthalmol. 1993;38:1–3 .

Whitacre MM, Stein RA, Hassanein K. The defect of corneal thickness on applanation tonometry. Am J Ophthalmol. 1993;115:592–6.

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Published

2023-03-14

How to Cite

Nkanga, D. G., Ibanga, A. A., Nkanga, E. D., Etim, B. A., Nwachukwu, K., & Ogba, P. O. (2023). Central Corneal Thickness (CCT) in Open Angle Glaucoma and Glaucoma Suspects in Calabar, Nigeria: Glaucoma. Transactions of the Ophthalmological Society of Nigeria, 1(1). Retrieved from https://tosn.org.ng/index.php/home/article/view/107