Bilateral Optic Atrophy Following Methanol Poisoning: A Case Report

Neuro Ophthalmology

Authors

  • Onua A.A Department of Ophthalmology, University of Port Harcourt Teaching Hospital, P.M.B.6173, Port Harcourt, Nigeria.
  • Nwadiuto I.C Epidemiology Unit, Rivers State Ministry of Health, Port Harcourt, Nigeria.
  • Pedro-Egbe CN Department of Ophthalmology, University of Port Harcourt Teaching Hospital, P.M.B.6173, Port Harcourt, Nigeria.

Abstract

Background: In Nigeria, in May 2015, outbreak of methanol poisoning was reported in Rivers State. We hereby report one of the cases. 

Case Report: A 53-year old man presented to the ophthalmology clinic, University of Port Harcourt Teaching Hospital on account of  sudden loss of vision in both eyes, following consumption of a substance believed to be alcohol eight days before presentation. The  patient said that he had consumed about 400ml of illicit gin popularly called “ogogoro” with five of his friends in Woji town, a suburb of Port Harcourt. The estimated quantity of ogogoro consumed by his friends was 500- 600ml each. The friends took ill after  consuming the said product and died within 5-24 hours. The index patient developed vomiting, headache and diminution of vision  about2-3 hours after consumption of the toxic product. Past ocular and medical history were not contributory. There was no history of  glaucoma or blindness in the family. On ocular examination the visual acuity was Hand  Motion (HM) in both eyes. The pupils were  idely dilated and there was no reaction to in both eyes. Fundoscopy showed bilateral optic atrophy and this was confirmed by fundus  photography. Laboratory investigations revealed normal  complete blood count, fasting blood sugar, renal and hepatic functions.  Arterial Blood Gas (ABG) analysis revealed metabolic acidosis with a pH of 7.16, pCO2 -16.2mmHg, HCO3 -6.1 meq/L, Na+- 146 meq/L,  K+- 4.1meq/L and Cl- -110.9 meq/L. In view of suspicion of illicit toxic alcohol ingestion, epidemiological report of methanol poisoning outbreak in Rivers State, acute visual loss, metabolic acidosis and fundus photographic findings, the clinical diagnosis of methanol poisoning was entertained which met the diagnostic criteria listed in Table 1. The patient refused hospital admission because of financial constraints. He was however treated with sodium bicarbonate, folic acid, hydroxocobalamin, prednisolone and multivitamin  tablets and advised to eat a well-balanced diet and abstain from drinking alcoholic beverages and smoking cigarettes. Patient was however lost to follow up so we do not know if there was any improvement in vision  

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Published

2023-03-24

How to Cite

A.A, O., I.C, N., & CN , P.-E. (2023). Bilateral Optic Atrophy Following Methanol Poisoning: A Case Report: Neuro Ophthalmology. Transactions of the Ophthalmological Society of Nigeria, 1(1). Retrieved from https://tosn.org.ng/index.php/home/article/view/147