Ocular Toxoplasmosis among Livestock Farmers and Raw Meat Handlers in Uyo, Nigeria

E. G. Abraham; A. E. Moses; U. S. Ekanem; O. O Motilewa; A. I Uwah; E. I Itina; A Umoh

Authors

E. G. Abraham Department of Ophthalmology, University of Uyo Teaching Hospital, Uyo, Nigeria
A. E. Moses Department of Microbiology, University of Uyo Teaching Hospital, Uyo, Nigeria
U. S. Ekanem Department of Community Health University of Uyo Teaching Hospital, Uyo, Nigeria
O. O Motilewa Department of Community Health University of Uyo Teaching Hospital, Uyo, Nigeria
A. I Uwah Department of Ophthalmology, University of Uyo Teaching Hospital, Uyo, Nigeria
E. I Itina Department of Ophthalmology, University of Uyo Teaching Hospital, Uyo, Nigeria
A Umoh Department of Microbiology, University of Uyo Teaching Hospital, Uyo, Nigeria

Abstract

Toxoplasmosis is the most common cause of infectious posterior uveitis in humans and can lead to low vision and blindness. ¹ Cats are the definitive host of Toxoplasma gondii.² Serological studies estimate that 30-50% of the global population has been exposed to and may be chronically infected with T. gondii.³Most infections in Africa are acquired through improperly cooked contaminated meat, unwashed contaminated fruits, vegetables, meat chopping boards and unwashed contaminated hands, and by contact with infected cat droppings.⁴ The seroprevalence of Toxoplasma gondii IgGvaries from 14% in USA to as high as 98% in southern Brazil.^5,6 In Nigeria, 28.7%seroprevalence of T. gondii infection has been reported in healthy adults and 37.8% to 54.2% among HIV-positive persons. This study aimed to determine the prevalence of ocular toxoplasmosis and potential risk factors amongst livestock farmers and raw meat handlers in Uyo, Nigeria.

References

Saadatnia G, Golkar M. A review on human toxoplasmosis. Scand J Infect Dis 2012; 44 (11): 805-14.

Jabs DA. Ocular toxoplasmosis. Int Ophthalmol Clin 1990; 30 : 64-270.

Pappas G, Roussons N, Falagas ME. Toxoplasmosis snapstots: global status of Toxoplasma gondii seroplrevalence and implications for pregnancy and congenital toxoplasmosis. Int J Parasitol 2009; 39 (12) : 1385-394.

Bahia-Oliveira LM, Jones JL, Azevedo-Silva J, Alves CCF, Orefice F, Addiss DG. Highly endemic waterborne toxoplasmosis in north Rio

de Janeiro state, Brasil. Emerg Infect Dis 2003; 9: 55-62. 34

Jones JL, Kruszon-Moran D, Sanders-Lewis K, Wilson M. Toxoplasma gondii infection in the U.S., 1999-2004, decline from then prior decade. Am J Trop Med Hyg 2007; 77 :405-410.

Silveiria C, Belfort R Jr., Burnier M Jr, Nussenblatt R. Acquired toxoplasmic infection as the cause of toxoplasmic retinochoroiditis in families. Am J Ophthalmol 1988; 106 : 362-364.

Kamani J, Aliyu M and Egwu GO. Seroprevalence of Toxoplasmosis gondii infection in dometic sheep and goats in Borno state, Nigeria. Trop

Anim Health Prod 2010; 42 : 793-97

Abu EK, Boampong JN, Amoabeng JK, Ilechie AA, Kyei S., Owusu-Ansah A et al. Epidemiology of Ocular Toxoplasmosis in Three Community

Surveys in the Central Region of Ghana, West Africa. Ophthalmic Epidemiol 2016; 23 (1) : 14-19.

London NJ, Hovakimyan A, Cubillan LD, Siverio CD Jr, Cunningham ET Jr. Prevalence, clinical characteristics, and causes of vision loss in

patients with ocular toxoplasmosis. Eur J Ophthalmol 2011; 21 (6) : 811-819.

Ferreira AI, Brandão De Mattos CC, Frederico FB, Meira CS, Almeida GC, Jr. Nakashima F, et al. Risk factors for ocular toxoplasmosis in Brazil. Epidemiol Infect 2013; 142 (1) : 142–148.