Challenges of Retinoblastoma Management in a Nigerian Tertiary Eye Care Facility
Orbit And Oculoplasty
Abstract
Introduction: Retinoblastoma is the most common primary intraocular tumor of childhood[1] . As a result of advances in treatment and early presentation, survival of retinoblastoma is >90% in developed countries[2] Globe-preserving treatment modalities have therefore become the trend in recent years[3]. In developing countries, the survival of patients with retinoblastoma is much lower[4]. This study aims to present the clinical profile and treatment outcome of patients with retinoblastoma managed at Guinness Eye Centre, Lagos University Teaching Hospital highlighting the challenges with a view to improving the management of the disease.
Methods: Retrospective chart review of patients diagnosed with retinoblastoma between January 2012 and December 2015. Data obtained from case files of patients include demographic characteristics, presenting complaint, laterality of disease, tumor stage using the International Intraocular Retinoblastoma Classification[5] , treatment and outcome. Data analysis was done using the Statistical Package for Social Sciences (SPSS) version 20 ( IBM Corporation 2011).
References
Kaposi M. Idiopathisches Multiples Pigmentsarkum der Haut. Arch DermatolSyphilol1872; 4: 265-73
Pantanowitz L, Dezube BJ. Kaposi Sarcoma in Unusual Locations. BMC Cancer 2008; 8: 1905
Collaço L, Gonçalves M, Gomes L, Miranda R. Orbital Kaposi’s Sarcoma in Acquired Humanimmunodeficiency Syndrome. Eur J Ophthalmol 2000; 10(1): 88-90
Nnoruka EN. Epidemic (Human Immunodeficiency Virus-related) Kaposi’s Sarcoma in West African Women. Int J Dermatol 2003; 42(10): 794- 799
Curtis TH, Durairaj VD. Conjunctival Kaposi sarcoma as the initial presentation of human immunodeficiency virus i n f e c t i o n . O p h t h a l P l a s t R e c o n s t r Surg. 2005;21:314–315.
Guo HX, Huang K, Zhou DH, Wang L, Xiao JH, Weng WJ, Fang JP. Acute Leukaemia in a Child with Ocular Kaposi’s Sarcoma After Hematopoietic Stem Cell Transplantation: A Case Report and Literatures Review. ZhonghuaXue Ye XueZaZhi 2013; 34(5): 445-458
Iroezindu O, Achusi IB. Classical Kaposi’s Sarcoma in a Nigerian Farmer: A Case Report. Eurosian J Med 2015; 47: 158-60.
Asuquo M, Umana A, Otei O, Bassey I, Ebughe G. Kaposi Sarcoma in Calabar, Southern Nigeria. Oman Med J 2009; 24(1): 33-6.
Mohammed AZ, Nwana EJC, Manasseh An. Changing Patterns of Kaposi’s Sarcoma in Nigerians. Trop Doct 2005; 35(3): 168-9
Tur E, Brenner S. Treatment of Kaposi’s sarcoma. Arch Dermatol. 1996;132:327– 331.
Jan RA, Koul PA, Ahmed M, Shah S, Mufti SA, War FA. Kaposi Sarcoma in a Non HIV Patient. International Journal of Health Sciences. 2008;2(2):153-156.
Gottlieb JJ, Washenik K, Chachua A, Kien AF. Treatment of classic Kaposi’ sarcoma with liposomal encapsulated doxorubicin. Lancet. 1997;350(8):1363–4
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Transactions of the Ophthalmological Society of Nigeria
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
